Workshop 2

The interplay of microcirculation and plasticity after ischemic stroke (Lecture Hall E11)

The consequences of ischemic stroke can be minimized by interventions in the acute phase that aim at re-establishing circulation and tissue perfusion. However, not everybody benefits from recanalization. Opening of a large vessel does not automatically improve microcirculation on the tissue level. Besides vessel patency, microcirculation is influenced by collateral blood supply to the territory of the occluded/recanalized large artery, by the degree of reperfusion injury and by cerebrovascular reactivity (CVR).

This workshop introduces the new CRPP Stroke, in which we aim to investigate the relationship between microcirculation, collateral perfusion, CVR and neuroplasticity, the evolution of these factors over time after stroke and their predictive value for recovery. 

Introduction and Moderation
Prof. Susanne Wegener, Department of Neurology, USZ

10:00 - 10:15

Connectivity changes after stroke: how much and how functional?
Dr. Meret Branscheid, Department of Neurology, USZ

10:15 - 10:30

Impact of collaterals on reperfusion and outcome in stroke
Dr. Mohamad El Amki, Department of Neurology, USZ


10:30 - 11:00

The cerebral collateral circulation: genetics, stroke, high-altitude and neurovascular coupling     
Prof. James Faber, Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill

11:00 - 11:15

Application of BOLD-CVR in acute stroke
Dr. Bas Van Niftrik, Department of Neurosurgery, USZ

11:15 - 11:30

Brief update on functional imaging in stroke
PD Dr. Lars Michels, Department of Neuroradiology, USZ