Workshop 3

Pain – concepts and circuits (Lecture Hall F1)

Chronic pain has an estimated prevalence at about 19% in the general society, likely to further increase due to demographic and lifestyle changes. Independent of the diverse clinical presentations, plastic changes at the level of individual neurons and neuronal circuits are a common theme occurring along the pain pathway. This workshop introduces the new CRPP “Pain – from phenotypes to mechanisms”, which addresses the interplay of peripheral, spinal and supra-spinal plasticity in chronic pain. Four speakers will present their views on neurophysiological and computational concepts of pain and the underlying neurobiological mechanisms in patients and in mice.

10:00 - 10:05

Introduction
Prof. Hanns Ulrich Zeilhofer, Institute of Pharmacology and Toxicology, UZH

10:05 - 10:45

The construction of pain: from nociception to conscious sensation
Prof. Luis Garcia-Larrea, Centre for Neuroscience, University of Lyon
 

10:45 - 11:00

Bayesian models of nociception
Matthias Müller-Schrader, Translational Neuromodeling Unit, UZH/ETHZ
 

11:00 - 11:15

Central pain in patients: from phenotype to mechanisms
Dr. Jan Rosner, Spinal Cord Injury Center, Balgrist University Hospital, UZH

11:15 - 11:30

Let’s get physical: neurons and circuits of descending pain modulation
Dr. Karen Haenraets, Institute of Pharmacology and Toxicology, UZH